RNA Details
Disease Name
diabetic cardiomyopathy
Tissue
heart
RNA Symbol
miR-340-5p
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
NA
Target
Mcl-1
Pathway
NA
PubMed ID
Title
miR-340-5p Mediates Cardiomyocyte Oxidative Stress in Diabetes-Induced Cardiac Dysfunction by Targeting Mcl-1
Year
2022
Function
"Mcl-1 as a major target gene for miR-340-5p and showed that the inhibition of Mcl-1 was responsible for increased functional loss of mitochondria, oxidative stress, and cardiomyocyte apoptosis"